Cyspera Intensive System™, the New Gold Standard solution to hyperpigmentation

Cyspera Intensive System is a novel clinically proven solution with fast and effective onset of action against hyperpigmentation without the concerns of Corticosteroids, Retinoic-Acid and Hydroquinone. Cyspera Intensive™ is formulated with Cysteamine Isobionic-Amide Complex™ to improve the appearance of persistent brown patches and dark spots.

Cyspera Intensive™

The Cysteamine Isobionic-Amide Complex™ delivers 3 powerful effects for improved pigment correction and skin health.

  • Cysteamine reduces melanin production in the melanogenesis pathway at multiple locations
  • Isobionic-Amide with AHA immediate reaction leads to instant pigment lightening in the corneal layer of the skin
  • AHA creates an acidic environment enhancing cysteamine permeability into the skin

Cyspera Neutralize

AHA-Amino Acid Complex re-balances the epidermis before application of Cyspera Boost™.

  • L-Arginine Complex stops the Isobionic-Amide / AHA reaction
  • As a Mild-Surfactant, it gently removes lingering residue while helping soothe the skin and promoting a healthy skin barrier
  • The Lactobionic Acid prepares the skin for Cyspera Boost™

Cyspera Boost

Cyspera Boost works synergistically with Cyspera Intensive to even skin tone, improve complexion and deliver a natural and healthy glow.

  • Cyspera Isobionic-Amide multiplies the efficacy of Cysteamine by further decreasing pigment formation on the skin
  • Retinol and an anti-oxidative complex provide visual pigment correction by speeding-up skin cell turnover
  • Cyspera Isobionic-Amide provides a soothing effect to the skin
  • Solar Lentigo
  • Hyperpigmented Scars
  • Rejuvenation
  • Senile Lentigo
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Before & After Results



















of subjects noticed Hyperpigmentation started to fade as early as 4 weeks and a smoother and more even skin tone

What to expect

The efficacy of Cyspera® is linked to the consistency of exposure over a period of time rather than the daily duration of exposure. Ensure to apply as indicated and start on unwashed face..

Some of Cyspera Intensive System clinically proven results include:

  • Fast Onset of Action for evening skin tone (within 4 weeks)
  • Significant efficacy
  • Fading of pigmented spots
  • No significant side effects
  • Maintenance of the results
  • Increased smoothness and skin hydration
  • Relief irritation prone skin

Hear from Patients & Doctors that use Cyspera®


Review Rating

Mika V USA

Best product for hyperpigmentation! I’ve used everything made for the last 2 years and this is the only product that has helped my dark pigment.

Minaz S USA

This cream has given me so much hope that I can’t even begin to describe it. Not only does it work, it also has zero side effects. Thank you!!

Hilary USA

Cyspera is a game changer. True science behind how it works. I have used it for 4 weeks and I can tell that there is 30% improvement to my dark patches.

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How to Use – 3 Step Routine

Use of Cyspera Intensive System can be tailored to meet the needs and routines of individual users. It can be applied in the morning or evening, offering flexibility and personalized choice.

Intensive phase: Once per day, everyday, for 16 weeks.

Maintenance phase: Once per day, twice-weekly.


Use Cyspera Intensive™ on unwashed skin. If you need to wash it (e.g., after a run), it is recommended to wait at least one hour before applying the product.


Step 1: Apply 1 pump of Cyspera Intensive to face and leave on for 5 – 15 minutes


Step 2: Before washing off Cyspera Intensive™, apply 2 pumps of Cyspera Neutralize™. Gently massage in circular motion, rinse thoroughly with water and pat dry


Step 3: Apply a thin layer of Cyspera Boost to face.


For optimal results, daily use of a broad spectrum sunscreen with SPF 30 or more is highly recommended.

Cyspera® is not phototoxic. It can be applied regardless of sun intensity and on any skin phototype.

Caution: For external use only. Do not use on damaged or irritated skin. Do not use in case of known allergy to a component. Discontinue use and ask a doctor if signs of irritation or allergy appear. Avoid contact with eyes. In case of eye contact, rinse off with clear water. Keep out of reach of children. Do not use for pregnant or lactating women. Use an adapted solar protection in case of sun exposure.

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